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Loulis (born May 10, 1978) is a chimpanzee who has learned to communicate in American Sign Language.

Loulis was named for two caregivers (Louise and Lisa) at the Yerkes Regional Primate Research Center in Atlanta, Georgia, where he was born. After ten months at Yerkes, Loulis was transferred to Oklahoma with Roger Fouts and Washoe, his adoptive mother. In 1980, the family moved to Central Washington University in Ellensburg, Washington. By 1993, the Chimpanzee and Human Communication Institute (CHCI) was built for the family to reside. Loulis's biological mother remained at Yerkes and was used for medical research. In 2013, he moved from the CHCI to the chimpanzee sanctuary of the Fauna Foundation in Canada.[1]